METHOD OF TREATING PATIENTS WITH SKIN CANCER WITH NEOPLASTIC PROCESSES INVOLVING SKIN TISSUE, SUCH AS MELANOMA, BASAL CELL AND SQUAMOUS CELL CARCINOMA (VERSIONS) Russian patent published in 2016 - IPC A61K35/30 A61K35/36 A61K38/17 A61P17/00 A61P35/00 

Abstract RU 2577135 C2

FIELD: medicine.

SUBSTANCE: tumour is sized up on the basis of which intracutaneous injections around an involved tissue prior to or after oncotomy are administered at 2-3 mm from its edge, or directly into a tumour tissue by introducing uniformly a medicinal product presented by 1.0-2.5 ml of a protein-polypeptide complex solution in a pharmaceutically acceptable carrier with the complex content (concentration) of 0.05-0.4 mg, by means of a reverse syringe needle 1-3 times a week, in the form of 6-20 injections within the therapeutic course of 4-14 procedures. The active substance is a protein-polypeptide complex produced of hoofed farm animal's nerve and skin embryonic tissue homogenate and containing negatively charged weak-acid and neutral proteins and polypeptides with molecular weight from 5 to 200 kDa and containing an average molecular weight fraction within 10 to 120 kDa of not less than 80%, with the total protein concentration of 0.2-4.2 mg/ml, the ultraviolet spectrum absorption peak of the solution at wave length 280±5 nm, the UV-visible spectrum peak at wave length 274-284 nm, the presence of specific bands in the range of pl from 4.2 to 8.4 in isoelectric focusing in 5% polyacrylamide gel. What is also presented is a method of treating the patients suffering skin cancer, such as melanoma, basal cell carcinoma, squamous cell carcinoma, wherein the above protein-peptide complex is used in the form of external applications.

EFFECT: treating the above skin diseases.

10 cl, 2 dwg, 6 ex

Similar patents RU2577135C2

Title Year Author Number
METHOD FOR PROPHYLACTIC TREATMENT IN CASE OFNEOPLASTIC PROCESSES INVOLVING SKIN TISSUE, SUCH AS MELANOMA, BASAL CELL AND SQUAMOUS CELL CARCINOMA 2015
  • Nazarenko Anna Borisovna
  • Sokolov Mikhail Anatolevich
RU2619208C2
PROTEIN-PEPTIDE ANTITUMOR COMPOSITION, CELL PREPARATION ACTIVATED THEREWITH AND METHOD FOR TUMOR PROPHYLAXIS OR TREATMENT 2004
  • Kalinina Ekaterina Sergeevna
  • Lutsenko Elena Valer'Evna
  • Lutsenko Sergej Viktorovich
  • Severin Evgenij Sergeevich
  • Severin Sergej Evgen'Evich
  • Fel'Dman Natalija Borisovna
  • Khomjakova Anastasija Viktorovna
RU2283129C1
VACCINE COMPOSITIONS, METHODS FOR APPLICATION THEREOF IN MELANOMA PREVENTION AND TREATMENT, AND GENETIC CONSTRUCTIONS FOR OBTAINING ACTIVE SUBSTANCES OF COMPOSITION 2006
  • Digtjar' Anton Vasil'Evich
  • Lutsenko Elena Valer'Evna
  • Lutsenko Sergej Viktorovich
  • Pozdnjakova Natal'Ja Vladimirovna
  • Severin Evgenij Sergeevich
  • Severin Sergej Evgen'Evich
  • Solov'Ev Andrej Ivanovich
  • Fel'Dman Natalija Borisovna
  • Khomjakova Anastasija Viktorovna
RU2333767C2
APPLICATION FOR TREATING AND PREVENTING ATHEROSCLEROSIS OF PROTEIN-PEPTIDE COMPLEX (HEREINAFTER PPC) OBTAINED FROM EMBRYONIC NERVE TISSUE OR OF QUICK FROZEN EMBRYO BRAIN OF FARM HOOFED ANIMALS AFFECTING CHECK TRANSPORT CHOLESTEROL FROM VASCULAR WALL AND PROFILE OF ACTIVATION OF MONOCYTES IN PATIENTS WITH MANIFESTED ATHEROSCLEROSIS OF GREAT VESSELS OR WITH PREDISPOSITION TO CARDIOVASCULAR DISEASES AND METHOD FOR PREVENTING AND TREATING PATIENTS WITH ARTERIAL ATHEROSCLEROSIS AND DISEASES CAUSED BY ATHEROSCLEROSIS OF MAJOR AND PERIPHERAL VASCULAR CEREBRAL, HEART, AORTA AND LOWER EXTREMITIES (TWO VERSIONS) 2014
  • Nazarenko Anna Borisovna
RU2586286C2
PROTEIN-POLYPEPTIDE COMPLEX POSSESSING TISSUE-SPECIFIC REGENERATIVE-REPARATIVE AND REJUVENATING ACTION ON SKIN TISSUE, METHOD FOR PREPARING IT, AND PHARMACEUTICAL COMPOSITION THEREOF 2011
  • Nazarenko Anna Borisovna
  • Sokolov Mikhail Anatol'Evich
RU2485133C2
APPLICATION OF FUNGICIDE AS AGENT FOR TREATING ONCOLOGIC DISEASES 2007
  • Kutushov Mikhail Vladimirovich
RU2381027C2
PROTEIN-POLYPEPTIDE COMPLEX (PPC) POSSESSING TISSUE SPECIFIC REPAIR AND REJUVENATING ACTION ON SKIN TISSUE, METHOD FOR PREPARING PROTEIN-POLYPEPTIDE COMPLEX POSSESSING TISSUE SPECIFIC REPAIR AND REJUVENATING ACTION ON SKIN TISSUE, AND PHARMACEUTICAL COMPOSITION OF PPC POSSESSING ANTIHYPOXIC, IMMUNOMODULATORY, TISSUE SPECIFIC REPAIR AND REJUVENATING ACTION ON SKIN TISSUE AND MUCOUS MEMBRANES, WITH REJUVENATING EFFECT 2011
  • Nazarenko Anna Borisovna
  • Sokolov Mikhail Anatol'Evich
RU2460736C1
METHOD OF THERAPY OF MALIGNANT DISEASES 2013
  • Ishchenko Aleksandr Mitrofanovich
  • Simbirtsev Andrej Semenovich
  • Margulis Boris Aleksandrovich
  • Guzhova Irina Vladimirovna
  • Shevtsov Maksim Alekseevich
RU2597414C2
MEDICINAL AGENT FOR ONCOTHERAPY 2008
  • Kutushov Mikhail Vladimirovich
RU2360686C1
PHARMACEUTICAL COMPOSITION BASED ON TRIINDOLYLMETHANE DERIVATIVE AS ANTI-TUMOUR MEDICATION 2012
  • Lavrenov Sergej Nikolaevich
  • Stepanova Evgenija Vladislavovna
  • Solomko Ehliso Shalikovna
  • Inshakov Andrej Nikolaevich
  • Treshchalin Ivan Dmitrievich
  • Bychkova Elena Nikolaevna
  • Preobrazhenskaja Marija Nikolaevna
RU2549430C2

RU 2 577 135 C2

Authors

Nazarenko Anna Borisovna

Sokolov Mikhail Anatolevich

Dates

2016-03-10Published

2014-07-01Filed