FIELD: bioengineering.
SUBSTANCE: antibodies are specifically linked with the domain S1 C4.4a, are cross-reactive in relation to C4.4a rodents, and are internalised after linking with the cells expressing C4.4a. The invention can be used for the medical treatment and diagnostics of abnormalities and states linked with the C4.4a overexpression.
EFFECT: invention ensures the method of producing of the said antibodies, the conjugate of the said antibody with a pharmaceutical.
18 cl, 7 dwg, 18 tbl, 15 ex
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Authors
Dates
2016-03-20—Published
2010-12-08—Filed