FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry. Described is an antibody or its antigen-binding fragment which specifically binds to human c-Met protein. Also described is an isolated polynucleotide coding said antibody, an expression vector containing said polynucleotide, a host cell containing said vector. Disclosed is a method of producing a recombinant antibody by culturing described host cell. Disclosed is a pharmaceutical composition for treating cancer and an immunoconjugate containing described antibody. Disclosed is a method of treating cancer involving administering described antibody.
EFFECT: invention widens range of agents for treating cancer.
15 cl, 25 dwg, 16 tbl, 26 ex
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