FIELD: biotechnology.
SUBSTANCE: present invention relates to an anti-PD-L1 antibody, antigen-binding fragments and their medical use. Additionally, the present invention refers to chimeric antibodies and humanised antibodies containing CDR-regions of this PD-L1 antibody, as well as to a pharmaceutical composition containing said PD-L1 antibody and antigen-binding fragments thereof, and to use thereof as antitumour agents. In particular, the present invention refers to a humanised anti-PD-L1 antibody and to its use for preparing a drug for treating a PD-L1-mediated disease or disorder.
EFFECT: invention widens the range of products for treating PD-L1-mediated disease or disorders.
23 cl, 10 tbl, 3 dwg, 4 ex
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