FIELD: chemistry.
SUBSTANCE: invention relates to composition for support of platelet function, wherein composition as active ingredient contains compound, represented by general formula (I), or its pharmaceutically acceptable salt: (I), wherein compound, represented by general formula (I), represents any of N-[2-(4-but-2-inyloxybenzenesulphonyl)-1-(4-diethylaminomethylphenyl)ethyl]-N-hydroxyformamide and N-{4-[2-(4-but-2-inyloxybenzenesulphonyl)-1-(formylhydroxyamino)ethyl]benzyl}methanesulphonamide. The invention also relates to method for obtaining platelets, culture medium, blood preparation and to method for supporting function of platelets in blood preparation.
EFFECT: composition for supporting function of platelets by specific inhibition of metalloproteinase ADAM17 activity is obtained.
7 cl, 3 tbl, 29 dwg, 44 ex
Title | Year | Author | Number |
---|---|---|---|
N-HYDROXYFORMAMIDE DERIVATIVE AND MEDICATION CONTAINING IT | 2011 |
|
RU2569851C2 |
PIPERIDINE- AND PIPERAZINE-SUBSTITUTED N-HYDROXYFORMAMIDES AS INHIBITORS OF METALLOPROTEINASES | 2001 |
|
RU2283306C2 |
METHOD FOR PRODUCING HIGH-FUNCTION THROMBOCYTES | 2016 |
|
RU2724533C2 |
NEW COMPOUND AND PHARMACEUTICAL COMPOSITION FOR INCREASING ANTICANCER ACTIVITY, CONTAINING SAID COMPOUND | 2019 |
|
RU2781282C1 |
COMPOUNDS AND COMPOSITIONS AS TRO MIMETICS | 2006 |
|
RU2385865C2 |
NEW COMPOUND AND A PHARMACEUTICAL COMPOSITION CONTAINING THE COMPOUND FOR THE PREVENTION OR TREATMENT OF CANCER | 2020 |
|
RU2801811C1 |
ANTIBACTERIAL AGENT | 2000 |
|
RU2269525C2 |
SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS | 2011 |
|
RU2606514C2 |
CARBAZOLE-CONTAINING AMIDES, CARBAMATES AND CARBAMIDES AS MODULATORS OF CRYPTOCHROMES | 2015 |
|
RU2705094C2 |
METHOD FOR THE PRODUCTION OF PLATELETS BY A METHOD FOR ROTATIONAL MIXING OF THE CULTURE | 2016 |
|
RU2756000C2 |
Authors
Dates
2016-03-27—Published
2011-09-16—Filed