COMPOSITION FOR SUPPORTING FUNCTION OF PLATELETS Russian patent published in 2016 - IPC A61K31/16 A61K31/4453 A61K31/5375 A61K35/14 A61K47/20 A61K47/22 C07C317/32 C07D295/12 C12N1/00 C12N5/73 C12N5/78 C12N5/10 

Abstract RU 2578607 C2

FIELD: chemistry.

SUBSTANCE: invention relates to composition for support of platelet function, wherein composition as active ingredient contains compound, represented by general formula (I), or its pharmaceutically acceptable salt: (I), wherein compound, represented by general formula (I), represents any of N-[2-(4-but-2-inyloxybenzenesulphonyl)-1-(4-diethylaminomethylphenyl)ethyl]-N-hydroxyformamide and N-{4-[2-(4-but-2-inyloxybenzenesulphonyl)-1-(formylhydroxyamino)ethyl]benzyl}methanesulphonamide. The invention also relates to method for obtaining platelets, culture medium, blood preparation and to method for supporting function of platelets in blood preparation.

EFFECT: composition for supporting function of platelets by specific inhibition of metalloproteinase ADAM17 activity is obtained.

7 cl, 3 tbl, 29 dwg, 44 ex

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RU 2 578 607 C2

Authors

Eto Kodzi

Okhnisi Rioko

Nakauti Khiromitsu

Murata Takakhiko

Dates

2016-03-27Published

2011-09-16Filed