FIELD: chemistry.
SUBSTANCE: invention relates to composition for support of platelet function, wherein composition as active ingredient contains compound, represented by general formula (I), or its pharmaceutically acceptable salt:
(I), wherein compound, represented by general formula (I), represents any of N-[2-(4-but-2-inyloxybenzenesulphonyl)-1-(4-diethylaminomethylphenyl)ethyl]-N-hydroxyformamide and N-{4-[2-(4-but-2-inyloxybenzenesulphonyl)-1-(formylhydroxyamino)ethyl]benzyl}methanesulphonamide. The invention also relates to method for obtaining platelets, culture medium, blood preparation and to method for supporting function of platelets in blood preparation.
EFFECT: composition for supporting function of platelets by specific inhibition of metalloproteinase ADAM17 activity is obtained.
7 cl, 3 tbl, 29 dwg, 44 ex
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Authors
Dates
2016-03-27—Published
2011-09-16—Filed