METHOD FOR PREDICTION OF ENDOMETRIAL RECEPTIVITY BASED ON EVALUATION OF EXPRESSION AND INTRACELLULAR LOCALISATION OF EZRIN IN STERILE WOMEN AND REPEATED FAILURES OF IVF PROGRAM Russian patent published in 2016 - IPC G01N33/53 

Abstract RU 2580629 C1

FIELD: medicine.

SUBSTANCE: invention can be used to predict receptivity of endometrium for infertility in women with repeated failure of IVF programs. Method comprises determining level of expression of ezrin and its intracellular localisation in biopsy of endometrium secondary stage secretion phase. During "window of implantation" receptor has an average stage endometrium secretion phase mature pinopodes more than 20 % of surface epithelium, and high levels of expression in the epithelium and ezrin and pinopodes.

EFFECT: invention allows predicting pregnancy in IVF and natural cycles in women with infertility.

1 cl, 6 dwg, 2 ex

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RU 2 580 629 C1

Authors

Kogan Evgenija Altarovna

Demura Tatjana Aleksandrovna

Seidova Ljaman Arif Kyzy

Perminova Svetlana Grigorevna

Dates

2016-04-10Published

2015-05-15Filed