METHOD FOR PREVENTING HUMORAL REJECTION IN CASE OF ABO INCOMPATIBILITY OF LIVER TRANSPLANTATION IN YOUNG CHILDREN Russian patent published in 2016 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to transplant, it may be used in preparing young children to the ABO-incompatible liver transplantation. Titer reduction of group-specific antibodies is carried out by daily transfusions of fresh frozen plasma group AB(IV) in a volume of 60-300 ml. Control group specific titers of antibodies capable of reacting with group agglutination antigens of the donor and transplantation is performed when the allowable level for transplantation controlled antibodies. Acceptable for transplantation titer of antibodies find natural group-specific antibodies is not more than 1:8, group-titer immune complete antibodies not more than 1:4 and incomplete group-immune titers of antibodies is not more than 1:4.

EFFECT: technical result achieved when exercising this inventive method consists in the prevention of complications caused by plasmapheresis, while maintaining a reliable high titer reduction of group-specific antibodies prior to transplantation, reducing the cost of the process, its availability.

3 cl, 3 ex