AGONISTS OF PROTEIN TYROSINE PHOSPHATASE-1 CONTAINING HOMOLOGY-2 SRC DOMAIN, AND METHODS OF TREATING USING SAID AGONISTS Russian patent published in 2016 - IPC C07C255/59 C07C275/18 C07C275/36 C07C311/21 C07D213/81 C07D215/233 C07D215/40 C07D471/04 A61K31/275 A61K31/44 A61K31/47 A61K31/437 A61P35/00 

FIELD: pharmaceutics.

SUBSTANCE: in formula I R₁ and R₃ independently represent hydrogen, and R₂ represents , , , , or R₁ independently represents hydrogen, R₃ is methyl, and R₂ represents or or R₂ and R₃ independently represent hydrogen, and R₁ is . Invention also refers to pharmaceutical compositions containing said compound, a method for increasing Src homology-2 containing proteintyrosinephosphatase-1 (SHP-1) expression in a cell, method of treating diseases or pathological condition characterised by low expression SHP-1, and to use of said compounds for preparing a drug for treating diseases or pathological condition characterised by low expression of SHP-1.

EFFECT: disclosed are novel compounds of formula I, having Src homology-2 containing protein tyrosine phosphatase-1 (SHP-1) agonist activity.

11 cl, 6 tbl, 23 dwg, 2 ex