FIELD: chemistry.
SUBSTANCE: invention relates to a compound of structural Formula II or a pharmaceutically acceptable salt thereof. In Formula II two of X2, X4 and X5 are N; and one of X2, X4 and X5 is O; or one of X2, X4 and X5 is N; one of X2, X4 and X5 is O; and one of X2, X4 and X5 is CH; Z1 and Z2 are independently selected from a group consisting of N, NR1, C=O and CR1; at least one of Z1 and Z2 is CR1; Z3 is selected from a group consisting of N, and CR12; values of remaining radicals are specified in the claim. Invention also relates to a compound of structural formula III, formula and values of radicals for which are specified in the claim, to individual compounds, to a pharmaceutical composition, to a method of treating diseases, to use of the compound as a medicinal agent.
EFFECT: obtaining novel compounds which can be useful as inhibitors of HIF cascade activity.
14 cl, 11 dwg, 2 tbl, 97 ex
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