FIELD: pharmaceutics.
SUBSTANCE: described is aqueous composition for instillation in urinary bladder based on hyaluronic acid and chondroitin sulphate. Composition also contains mannitol or sorbitol in relation to sum of hyaluronic acid and chondroitin sulphate, equal to 0.014-4.2. Said composition can additionally contain zinc chloride.
EFFECT: invention provides high protective effect on urothelium cells after oxidative stress and increased mediated antimicrobial action due to inclusion of mannitol or sorbitol in composition, high direct antimicrobial action and protection of urothelium due to inclusion of zinc chloride, as well as controlled viscosity due to inclusion of mannitol and zinc chloride.
1 cl, 4 tbl, 6 ex
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Authors
Dates
2016-06-10—Published
2015-03-24—Filed