PHARMACEUTICAL COMPOSITION FOR INHIBITING NEURONAL APOPTOSIS OR NEURODEGENERATION Russian patent published in 2016 - IPC A61K31/42 A61K31/4196 A61K31/4245 A61K31/433 A61P25/00 

FIELD: chemistry.

SUBSTANCE: invention relates to the use of compounds of formula I.

Formula I, wherein R represents C₇-C₁₅ phenylalkyl group; Y represents O; R₁ and R₂ They are H; A is O; B is C; Z is -OC (= O) NR₃R₄; each of R₃ and R₄ is H; m and n are 0, a pharmaceutically acceptable salt, isomer, solvate or hydrate or any combination thereof.

EFFECT: for the manufacture of a medicament for the prevention or treatment of diseases selected from the group consisting of stroke, Alzheimer's disease, Huntington's disease, Pick's disease, Creutzfeldt-Jakob disease, complex Parkinson-ALS-dementia, Wilson's disease, multiple sclerosis, progressive supranuclear palsy, bipolar disorders associated with neuropathic pain, cortico-basal degeneration, schizophrenia, hyperactivity with attention deficit (ADHD), dementia, amyotrophic lateral sclerosis, retinal disease, epilepsy, apoplexy, transient ischemic attack, myocardial ischemia, muscular ischemia, ischemia-induced surgery requiring prolonged cessation of blood flow to the brain, head injury, spinal cord injury, hypoxia, and depression.

3 cl, 12 ex, 1 tbl, 24 dwg