IMMUNOSTIMULATING OLIGODEOXYNUCLEOTIDES Russian patent published in 2016 - IPC C12N15/117 C12N15/76 A61K39/39 A61P37/04 

Abstract RU 2587633 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to obtaining immunostimulating oligodeoxynucleotides of general formula 5′[G]x{[T]pTTCGTC [T]q}n[G]z3′, where x = 3-10, z = 0-10, n = 2-100, p = 1-15, and can be used in veterinary science. Obtained immunostimulating oligodeoxynucleotides or vectors and therapeutic agents containing them can be used in vaccination against infectious diseases in poultry.

EFFECT: present invention enables stimulating activation of NF-kB and IRF3 transcription factors, as well as enhance expression involved in inflammatory process cytokines.

14 cl, 10 dwg, 5 ex

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RU 2 587 633 C2

Authors

Shrajer Karla Kristina

Ilg Tomas Zimon

Dates

2016-06-20Published

2012-05-25Filed