IMMUNOSTIMULATING OLIGODEOXYNUCLEOTIDES Russian patent published in 2016 - IPC C12N15/117 C12N15/79 A61P37/04 A61K39/39 

Abstract RU 2584588 C2

FIELD: animal breeding.

SUBSTANCE: present invention refers to immuno-stimulating oligodeoxynucleotides of general formula: 5' [G]x{TCG TCG}nTCG[G]z 3', where x = 3-20, z = 0-10, n = 2-100, and can be used in medicine, particularly in veterinary science. Obtained immuno-stimulating oligodeoxynucleotides or containing them vectors and therapeutic agents can be used for preventing infectious disease in poultry.

EFFECT: present invention enables stimulating activation of NF-kB and IRF3 transcription factors, as well as enhance expression involved in inflammatory process cytokines that promotes formation of active immunity to various infections in poultry.

9 cl, 10 dwg, 3 ex

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RU 2 584 588 C2

Authors

Shrajer Karla Kristina

Ilg Tomas Zimon

Dates

2016-05-20Published

2012-05-25Filed