FIELD: animal breeding.
SUBSTANCE: present invention refers to immuno-stimulating oligodeoxynucleotides of general formula: 5' [G]x{TCG TCG}nTCG[G]z 3', where x = 3-20, z = 0-10, n = 2-100, and can be used in medicine, particularly in veterinary science. Obtained immuno-stimulating oligodeoxynucleotides or containing them vectors and therapeutic agents can be used for preventing infectious disease in poultry.
EFFECT: present invention enables stimulating activation of NF-kB and IRF3 transcription factors, as well as enhance expression involved in inflammatory process cytokines that promotes formation of active immunity to various infections in poultry.
9 cl, 10 dwg, 3 ex
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Authors
Dates
2016-05-20—Published
2012-05-25—Filed