DETECTION, MEASUREMENT AND IMAGING OF CELLS, SUCH AS CANCER, AND OTHER BIOLOGICAL SUBSTANCES USING TARGETED NANOPARTICLES AND MAGNETIC PROPERTIES THEREOF Russian patent published in 2016 - IPC A61F2/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to the means of detecting and measuring cells or substances via targeted nanoparticles. Apparatus comprises a magnetizing subsystem for magnetization nanoparticles which are associated with one or more specified types of cancer cells, or biological substances in a patient, a sensor subsystem to detect the residual magnetic field in the region of interest of the patient after the unbound nanoparticles back to the random magnetization, and for a time nanoparticles of transition related to the random homogeneous magnetization, and the management and analysis of the residual magnetic field to detect, measure or determine the location of one or more specific types of cancer cells, or biological substances in a patient. Method uses a device and includes placing a plurality of targeted nanoparticles to the patient, wherein each of the plurality of targeted nanoparticles include paramagnetic nanoparticle conjugated to a targeting agent that binds to one or more specified types of cancer cells, or biological substances, the use of the magnetizing subsystem sensor subsystem and control system and analysis.

EFFECT: use of the invention allows early detection of tissue damage.

21 cl, 27 dwg