FIELD: medicine.
SUBSTANCE: method for prostate cancer diagnosis and a method for monitoring of the response to prostate cancer therapy, involving contacting of cancerous cells of epithelial origin with an anti-STEAP-1 antibody that specifically binds to the prostate-specific STEAP-1 marker with KD≤1000 nM, wherein the anti-STEAP-1 antibody is the 15A5 antibody produced by a hybridoma cell having a microbial deposition number PTA-12259.
EFFECT: effective methods for diagnosis and monitoring of prostate cancer.
17 cl, 11 dwg, 8 ex
Title | Year | Author | Number |
---|---|---|---|
CIRCULATING TUMOUR CELL ASSAY | 2007 |
|
RU2429486C2 |
METHODS OF DETECTING 5T4-POSITIVE CIRCULATING TUMOR CELLS AND METHODS OF DIAGNOSTICS OF 5T4-POSITIVE CANCER IN MAMMALS | 2013 |
|
RU2646498C2 |
GENETICALLY MODIFIED GAMMA DELTA T CELLS | 2015 |
|
RU2756247C2 |
NEW CANCER ANTIGEN FOR EARLY DETECTION OF CANCER, METHOD FOR OBTAINING, ISOLATION AND DETECTION THEREOF | 2020 |
|
RU2818471C2 |
ANTIBODIES AND IMMUNOCONJUGATES AND THEIR APPLICATIONS | 2007 |
|
RU2639543C9 |
METHOD FOR DETECTING TUMOUR CELLS CIRCULATING IN BLOOD BY MULTIPARAMETER FLOW CYTOMETRY | 2024 |
|
RU2825188C2 |
ANNEXIN A3 AUTOIMMUNE REGULATION OF PROSTATE CANCER | 2008 |
|
RU2484482C2 |
METHODS FOR PREDICTING PROSTATE CANCER | 2016 |
|
RU2760577C2 |
PHOSPHODIESTERASE 4D7 AS PROSTATE CANCER MARKER | 2010 |
|
RU2651474C2 |
REPRODUCTION AND USE OF NON-HEMATOPOIETIC TISSUE-RESIDENT γδ T-CELLS | 2016 |
|
RU2784566C2 |
Authors
Dates
2018-01-23—Published
2012-11-29—Filed