FIELD: medicine.
SUBSTANCE: method for prostate cancer diagnosis and a method for monitoring of the response to prostate cancer therapy, involving contacting of cancerous cells of epithelial origin with an anti-STEAP-1 antibody that specifically binds to the prostate-specific STEAP-1 marker with KD≤1000 nM, wherein the anti-STEAP-1 antibody is the 15A5 antibody produced by a hybridoma cell having a microbial deposition number PTA-12259.
EFFECT: effective methods for diagnosis and monitoring of prostate cancer.
17 cl, 11 dwg, 8 ex
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Authors
Dates
2018-01-23—Published
2012-11-29—Filed