NOVEL PEROXIDE DERIVATIVES, SYNTHESIS METHOD THEREOF AND USE THEREOF IN MEDICINE AND COSMETICS FOR TREATING OR PREVENTING ACNE IN INDIVIDUAL Russian patent published in 2016 - IPC C07C409/34 A61K8/38 A61Q19/00

Abstract RU 2588492 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to compounds of general formula (I). In said formula R1 represents (C₂-C₄)alkyl, (C₃-C₁₀)cycloalkyl, (C₃-C₁₀)cycloalkyl (C₂-C₄)alkyl, (C₂-C₄)alkoxy or (C₃-C₁₀)cycloalkyloxy; A is hydrogen or is a group -OC(O)R2, where R2 is (C₂-C₄)alkoxy or (C₃-C₁₀)cycloalkyloxy. Term "alkyl" denotes a saturated linear or branched hydrocarbon chain.

EFFECT: compounds of formula (I) inhibit proliferation of pathogenic microorganisms,involved in appearance of acne skin disorders, particularly P.acnes, and can be used for treating diseases and disorders associated with P.acnes.

4 cl, 12 ex

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RU 2 588 492 C2

Authors

Bui-Peter Kler

Paskal Zhan-Klod

Rodevill Nikolya

Dates

2016-06-27—Published

2010-12-10—Filed