FIELD: medicine, ophthalmology. SUBSTANCE: agent has an active component of the general formula (I): 
where X means a group of the formula 
or 
and R1, R2, R3, R4 have definite values. An agent is used locally into eyes at effective doses. EFFECT: enhanced effectiveness of an agent, decreased adverse responses. 25 cl, 4 ex, 1 tbl
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