FIELD: organic chemistry, medicine, ophthalmology.
SUBSTANCE: invention relates to an ophthalmic solution containing compound of the following chemical formula (I): wherein R1 represents group of the formula (Ia): or its pharmaceutically acceptable salt or derivative, cationic antiseptic agent and basic amino-compound wherein cationic antiseptic agent represents quaternary ammonium salt or chlorhexidine, and basic amino-compound represents at least one compound chosen from trometamol, lidocaine and nicotinamide. Quaternary ammonium salt represents benzalconium chloride, benzetonium chloride, cetylpyridinium or cetrimide. Ophthalmic solution can contain additionally boric acids, ethylenediaminetetraacetic acids. Owing the presence of additives the invention provides enhancing antiseptic effect of ophthalmic solutions.
EFFECT: improved and valuable medicinal properties of ophthalmic solutions.
11 cl, 4 tbl, 2 dwg, 7 ex
Authors
Dates
2008-03-10—Published
2003-03-10—Filed