FIELD: biochemistry.
SUBSTANCE: described is structure triplet of Treponema pallidum antigen, which includes three antigens to Treponema pallidum (TP15, TP17 and TP47), as well as leader sequence of ten amino acids (mark 261) and copper-zinc containing human superoxide dismutase (hSOD). This design is optimized for diagnosing syphilitic infection in vitro. Described also is plasmid containing DNA coding triplet antigen, host cells, methods of producing, methods for detection and sets.
EFFECT: invention extends range of agents and methods for determination of syphilis.
45 cl, 19 dwg, 8 tbl, 4 ex
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