METHOD OF HUMAN PROTEIN CXCL1 IMMUNOASSAY Russian patent published in 2014 - IPC C12N15/09 C07K16/18 C12P21/08 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention relates to biochemistry. A method of immunoassay of human protein CXCL1 is described. Human CXCL1 or its fragment is measured in a sample with application of two or more types of monoclonal antibodies to human CXCL1 or their fragments. Each of two or more types of the monoclonal antibodies to human CXCL1 or their fragments specifically identifies any of regions of a sequence of amino acid sequences, represented in SEQ ID NO:1-3, which represent partial sequences of an amino acid sequence, constituting human protein CXCL1. Two or more types of the monoclonal antibodies to human CXCL1 or their fragments specifically identify regions of the sequence, different from each other. Claimed are the monoclonal antibodies or their fragments, each of which specifically identifies any region of the amino acid sequence, represented in SEQ ID NO:1-3, and has a new amino acid sequence.

EFFECT: invention makes it possible to determine human protein CXCL1 with high sensitivity.

15 cl, 9 dwg, 1 tbl, 21 ex