FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and represents a modified polynucleotide coding aspartate kinase (LysC), where initiation codon of polynucleotide has been replaced with ATG. Invention also relates to an expression vector containing said modified polynucleotide, as well as to modified microorganisms of genus Corynebacterium for production of L-lysine, which has high activity as compared to its aspartate kinase endogenous activity, where initiation codon of polynucleotide encoding aspartate kinase has been replaced with ATG.
EFFECT: invention enables to obtain L-lysine with high yield.
9 cl, 10 tbl, 11 ex
| Title |
Year |
Author |
Number |
| METHOD FOR L-LYSINE PRODUCTION USING MICROORGANISMS CAPABLE OF L-LYSINE PRODUCTION |
2012 |
- Lee Kwang Ho
- Lim Sang Jo
- Moon Jun Ok
- Jang Jae Woo
- Park Su Jin
- Park Sang Hee
|
RU2616870C1 |
| METHOD FOR L-LYSINE PRODUCTION USING MICROORGANISMS CAPABLE OF L-LYSINE PRODUCTION |
2012 |
- Lee Kwang Ho
- Lim Sang Jo
- Moon Jun Ok
- Jang Jae Woo
- Park Su Jin
- Park Sang Hee
|
RU2615454C1 |
| MICROORGANISM OF CORYNEBACTERIUM SPECIES HAVING ENHANCED L-LYSINE PRODUCIBILITY AND METHOD FOR PRODUCING L-LYSINE USING SAME |
2014 |
- Park Sang Hee
- Moon Jun Ok
- Bae Hyun Won
- Lee Kwang Ho
|
RU2667425C2 |
| GLUCONATE REPRESSOR VARIANT, L-LYSINE MICROORGANISM-PRODUCER THEREWITH AND METHOD FOR OBTAINING L-LYSINE BASED THEREON |
2016 |
- Park Sang Hee
- Kim Hyung Joon
- Kim Nam Hyun
- Moon Jun Ok
- Oh Jeong Seok
- Ryu Song-Gi
- Choi Hyang
|
RU2681475C1 |
| METHOD OF PRODUCING AMINO ACIDS OF ASPARATE FAMILY WITH APPLICATION OF MICROORGANISMS |
2010 |
- Vittmann, Kristof
- Bekker, Judit
|
RU2535973C2 |
| CORYNEBACTERIUM SPECIES MICROORGANISMS, HAVING CAPACITIES TO PRODUCE L-LYSINE, AND METHOD FOR PRODUCING L-LYSINE USING SAID MICROORGANISMS |
2016 |
- Byun Hyo Jeong
- Chung Yoon Hee
- Kim Hyung Joon
- Lee Sun Young
- Nam Hyun Koo
- Park Sun Mi
- Lee Sang Mok
|
RU2685482C1 |
| CORYNEBACTERIUM GENUS MICROORGANISM WITH IMPROVED ABILITY TO PRODUCE L-LYSINE AND METHOD FOR PRODUCING L-LYSINE USING SAME |
2014 |
- Moon Jun Ok
- Park Sang Hee
- Huh Lan
- Lee Kwang Ho
|
RU2651505C1 |
| MICROORGANISM HAVING IMPROVED L-LYSINE PRODUCING ABILITY AND METHOD FOR PRODUCING L-LYSINE BY USING SAID MICROORGANISM |
2015 |
- Lee, Peter
- Moon, Jun Ok
- Kim, Hyung Joon
- Ryu, Song Gi
|
RU2663135C2 |
| MICROORGANISMS OF CORYNEBACTERIUM SP., CAPABLE OF PRODUCING L-LYSINE, AND A METHOD FOR PRODUCING L-LYSINE USING SAID MICROORGANISMS |
2016 |
- Lee, Seung Bin
- Chung, Yoon Hee
- Kim, Hyung Joon
- Kang, Doo Jin
- Bang, Seong Eun
- Ryu, Song Gi
|
RU2687206C1 |
| CORYNEBACTERIUM GENUS MICROORGANISM FOR PRODUCING L-LYSINE AND METHOD FOR PRODUCING L-LYSINE BY USING SAME |
2015 |
- Lee Seung Bin
- Kim Hyung Joon
- Hur Lan
- Moon Jun Ok
|
RU2668830C2 |
