FIELD: biotechnology.
SUBSTANCE: modified polynucleotide is proposed, encoding a transketolase (Tkt), wherein the initiating polynucleotide codon is replaced by ATG. An expression vector comprising the said modified polynucleotide is presented. Corynebacterium genus modified microorganism for L-lysine production is presented, which has an increased transketolase activity compared to its endogenous activity, where the initiating codon of the transketolase encoding polynucleotide is replaced by ATG.
EFFECT: group of inventions allows to obtain L-lysine with high productivity.
9 cl, 10 tbl, 11 ex
| Title |
Year |
Author |
Number |
| METHOD OF PRODUCING L-LYSINE USING MICROORGANISMS, CAPABLE OF PRODUCING L-LYSINE |
2012 |
- Lee Kwang Ho
- Lim Sang Jo
- Moon Jun Ok
- Jang Jae Woo
- Park Su Jin
- Park Sang Hee
|
RU2588665C2 |
| METHOD FOR L-LYSINE PRODUCTION USING MICROORGANISMS CAPABLE OF L-LYSINE PRODUCTION |
2012 |
- Lee Kwang Ho
- Lim Sang Jo
- Moon Jun Ok
- Jang Jae Woo
- Park Su Jin
- Park Sang Hee
|
RU2616870C1 |
| MICROORGANISM OF CORYNEBACTERIUM SPECIES HAVING ENHANCED L-LYSINE PRODUCIBILITY AND METHOD FOR PRODUCING L-LYSINE USING SAME |
2014 |
- Park Sang Hee
- Moon Jun Ok
- Bae Hyun Won
- Lee Kwang Ho
|
RU2667425C2 |
| GLUCONATE REPRESSOR VARIANT, L-LYSINE MICROORGANISM-PRODUCER THEREWITH AND METHOD FOR OBTAINING L-LYSINE BASED THEREON |
2016 |
- Park Sang Hee
- Kim Hyung Joon
- Kim Nam Hyun
- Moon Jun Ok
- Oh Jeong Seok
- Ryu Song-Gi
- Choi Hyang
|
RU2681475C1 |
| CORYNEBACTERIUM SPECIES MICROORGANISMS, HAVING CAPACITIES TO PRODUCE L-LYSINE, AND METHOD FOR PRODUCING L-LYSINE USING SAID MICROORGANISMS |
2016 |
- Byun Hyo Jeong
- Chung Yoon Hee
- Kim Hyung Joon
- Lee Sun Young
- Nam Hyun Koo
- Park Sun Mi
- Lee Sang Mok
|
RU2685482C1 |
| METHOD OF PRODUCING AMINO ACIDS OF ASPARATE FAMILY WITH APPLICATION OF MICROORGANISMS |
2010 |
- Vittmann, Kristof
- Bekker, Judit
|
RU2535973C2 |
| CORYNEBACTERIUM GENUS MICROORGANISM WITH IMPROVED ABILITY TO PRODUCE L-LYSINE AND METHOD FOR PRODUCING L-LYSINE USING SAME |
2014 |
- Moon Jun Ok
- Park Sang Hee
- Huh Lan
- Lee Kwang Ho
|
RU2651505C1 |
| MICROORGANISM HAVING IMPROVED L-LYSINE PRODUCING ABILITY AND METHOD FOR PRODUCING L-LYSINE BY USING SAID MICROORGANISM |
2015 |
- Lee, Peter
- Moon, Jun Ok
- Kim, Hyung Joon
- Ryu, Song Gi
|
RU2663135C2 |
| MICROORGANISMS OF CORYNEBACTERIUM SP., CAPABLE OF PRODUCING L-LYSINE, AND A METHOD FOR PRODUCING L-LYSINE USING SAID MICROORGANISMS |
2016 |
- Lee, Seung Bin
- Chung, Yoon Hee
- Kim, Hyung Joon
- Kang, Doo Jin
- Bang, Seong Eun
- Ryu, Song Gi
|
RU2687206C1 |
| CORYNEBACTERIUM GENUS MICROORGANISM FOR PRODUCING L-LYSINE AND METHOD FOR PRODUCING L-LYSINE BY USING SAME |
2015 |
- Lee Seung Bin
- Kim Hyung Joon
- Hur Lan
- Moon Jun Ok
|
RU2668830C2 |
