FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology, in particular, to method of producing amino acids derived from aspartate with application of recombinant microorganism, possessing at least the following properties in comparison with initial microorganism: (a) increased activity of glucose-6-phosphatedehydrogenase, (b) increased activity of fructose-1,6-biphosphatase, (c) weaker activity of isocitrate dehydrogenase, (d) increased activity of diaminopimelate dehydrogenase and (e) increased activity of aspartate kinase, where microorganism represents Corynebacterium.
EFFECT: invention makes it possible to produce amino acids of aspartate family, in particular L-lysine with high degree of efficiency.
15 cl, 35 dwg, 20 tbl, 1 ex
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Authors
Dates
2014-12-20—Published
2010-06-15—Filed