FIELD: pharmaceutics.
SUBSTANCE: pharmaceutical composition containing the compound 1,3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridine-2-yl)benzoic acid, and at least one excipient selected from filler, diluent, disintegrating agent, surfactant, binder, imparting slipperiness substance and lubricant, wherein composition is suitable for oral administration to patient in need thereof for treating CFTR-mediated diseases, such as cystic fibrosis. Methods of patient in need treating thereof include administering.
EFFECT: including compound 1 having oral pharmaceutical finished dosage form.
84 cl, 27 dwg, 18 tbl
| Title |
Year |
Author |
Number |
| SOLID FORMS OF 3-(2, 2-DIFLUOROBENZO[D][1,3] DIOXOL-5-YL)CYCLOPROPANCARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID |
2011 |
- Keskhavarz-Skhokri Ali
- Chzhan Bejli
- Kravets Mariush
|
RU2579370C2 |
| FORMULATIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZONIC ACID |
2013 |
|
RU2644723C2 |
| SOLID FORMS OF (R)-1-(2, 2-DIFLUOROBENZO[D][1, 3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL) CYCLOPROPANECARBOXAMIDE |
2011 |
- Keskhavarz-Skhokri, Ali
- Chzhan, Bejli
- Alkasio, Tim, Edvard
- Li, Elejn, Chungmin
- Chzhan, Yuegan
- Kravets, Mariush
|
RU2711481C2 |
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2011 |
- Keskhavarz-Skhokri Ali
- Chzhan Behjli
- Alkasio Tim Ehdvard
- Li Ehlejn Chungmin
- Chzhan Juehgan
- Kravets Mariush
|
RU2573830C2 |
| SOLID FORMS OF N-(4-(7-AZABICYCLO[2,2,1]HEPTAN-7-YL)-2-(TRIFLUOROMETHYL)PHENYL)-4-OXO-5-(TRIFLUOROMETHYL)-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE |
2010 |
- Chzhan Behjli
- Kravets Mariush
- Luizi Brajan
- Medek Ales
|
RU2568608C2 |
| PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES MEDIATED BY A TRANSMEMBRANE REGULATOR OF CYSTIC FIBROSIS (CFTR) |
2013 |
- Vervejs Marinus Yakobus
- Karkare Radkhika
- Mur Majkl Duglas
|
RU2692676C2 |
| METHOD OF PRODUCING PHARMACEUTICAL COMPOSITIONS FOR TREATING CFTR MEDIATED DISEASES |
2014 |
- Swinney, Kelly, Ann
- Hurter, Patricia, Nell
- Nadig, David, E.
- Smith, David
- Thomas, Vance, Hayden
- Warman, Martin, Paul
|
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| SOLID FORMS OF N-(7-AZABICYCLO[2,2,1]HEPTAN-7-YL-)-2-(TRIFLUOROMETHYL)PHENYL)-4-OXO-5-(TRIFLUOROMETHYL)-1,4-DIHYDROQUIINOLINE-3-CARBOXAMIDE |
2009 |
- Chzhan Behjli
- Kravets Mariush
- Botfild Martin
- Grotenkhejs Peter D J.
- Van Gur Fredrik
|
RU2518479C2 |
| PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES MEDIATED BY CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR |
2015 |
- Phenix, Brian, Dean
- Bagnol, Laurent, Jean-Claude
- Brodeur, Geoffrey, Glen
- Chandran, Sachin
- Dokou, Eleni
- Ferris, Lori, Ann
- Knezic, Dragutin
- Mccarty, Katie, Lynn
- Medek, Ales
- Waggener, Sara, A.
|
RU2744460C2 |
| CO-CRYSTALS OF TRANSMEMBRANE CONDUCTION REGULATOR MODULATORS IN CYSTIC FIBROSIS |
2015 |
- Strohmeier, Mark
- Caesar, Jr., John P.
- Connelly, Patrick Raymond
- Fawaz, Majed
- Luss-Lusis, Eduard
- Mcclain, Brian R.
- Medek, Ales
- Miao, Hai
- Nti-Addae, Kwame Wiredu
- Yin, Ping
- Zhang, Yuegang
|
RU2749213C2 |
