FIELD: chemistry.
SUBSTANCE: invention relates to a compound of formula
or a salt thereof.
EFFECT: technical result is obtaining a novel compound, which is intermediate for producing (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide, which in turn can be used in medicine for treating CFTR-mediated disease.
1 cl, 19 dwg, 13 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| SOLID FORMS OF (R)-1-(2,2-DIFLUOROBENZO[d][1,3]DIOXOL-5-YL)-N-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL)CYCLOPROPANE CARBOXAMIDE | 2011 |
|
RU2573830C2 |
| SOLID FORMS OF 3-(2, 2-DIFLUOROBENZO[D][1,3] DIOXOL-5-YL)CYCLOPROPANCARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID | 2011 |
|
RU2579370C2 |
| FORMULATIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZONIC ACID | 2013 |
|
RU2644723C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING 3-(2, 2-DIFLUOROBENZO[d][1, 3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDINE-2-YL)BENZOIC ACID, AND ADMINISTRATION THEREOF | 2011 |
|
RU2592368C2 |
| PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES MEDIATED BY CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | 2015 |
|
RU2744460C2 |
| METHOD OF PRODUCING PHARMACEUTICAL COMPOSITIONS FOR TREATING CFTR MEDIATED DISEASES | 2014 |
|
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| MODULATORS OF ATP-BINDING CARTRIDGE TRANSPORTERS | 2012 |
|
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|
RU2512682C2 |
| PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES MEDIATED BY A TRANSMEMBRANE REGULATOR OF CYSTIC FIBROSIS (CFTR) | 2013 |
|
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| CO-CRYSTALS OF TRANSMEMBRANE CONDUCTION REGULATOR MODULATORS IN CYSTIC FIBROSIS | 2015 |
|
RU2749213C2 |
