FIELD: chemistry.
SUBSTANCE: group of inventions concerns an isolated polynucleotide molecule of nucleic acid which codes North American porcine reproductive and respiratory syndrome (PRRS) virus, a host cell for generation of PRRS virus, transfected by said polynucleotide molecule, vaccine for protection of pigs against infection with PRRS virus, RNA molecule coding PRRS virus, method of generating a PRRS virus in vitro and plasmid for expression of PRRS virus. Described isolated nucleic acid molecule has a sequence presented in SEQ ID NO: 1, 2, 3, 4 or 6.
EFFECT: disclosed group of inventions enables to obtain an effective immune response in pigs to North American porcine reproductive and respiratory syndrome virus and can be used in veterinary science.
10 cl, 8 dwg, 10 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOSITION FOR PIGS PROTECTION AGAINST PRRS-VIRUS INFECTION (VERSIONS) AND VACCINE CONTAINING SPECIFIED COMPOSITION (VERSIONS) | 2006 |
|
RU2381035C2 |
| EFFECTIVE VACCINATION AGAINST EUROPEAN STRAINS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRS) BEFORE WEANING | 2017 |
|
RU2755345C2 |
| PRRS VIRUSES, THEIR INFECTIOUS CLONES, MUTANT FORMS AND METHODS OF APPLICATION | 2006 |
|
RU2427646C2 |
| COMBINATION VACCINE PCV/MYCOPLASMA HYOPNEUMONIAE/PRRS (PCV/MYCOPLASMA HYOPNEUMONIAE/PRRS COMBINATION VACCINE) | 2013 |
|
RU2644256C2 |
| MYCOPLASMA HYOPNEUMONIAE VACCINE | 2013 |
|
RU2644254C2 |
| CHIMERIC PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND VACCINE USING SAID VIRUS | 2019 |
|
RU2781446C1 |
| COMBINED VACCINE PCV/MYCOPLASMA HYOPNEUMONIAE | 2013 |
|
RU2615443C2 |
| IMMUNOGENIC COMPOSITIONS FOR IMMUNIZATION OF PIGS AGAINST CIRCOVIRUS TYPE 3 AND METHODS OF PRDUCTION AND APPLICATION THEREOF | 2016 |
|
RU2744193C2 |
| EXTRACTED POLYNUCLEOTIDE MOLECULE CODING Torque teno VIRUS, RNA MOLECULE AND EXPRESSION VECTOR | 2009 |
|
RU2502801C2 |
| PCV2B DIVERGENT VACCINE COMPOSITION AND METHODS OF USE | 2014 |
|
RU2662685C2 |
