SORBENT FOR SEPARATION OF OPTICAL ISOMERS OF SUBSTANCES AND ANALYSIS THEREOF IN BIOLOGICAL FLUIDS BY HPLC AND PREPARATION METHOD THEREOF Russian patent published in 2016 - IPC B01J20/29 B01J20/283 B01J20/286 

Abstract RU 2592893 C2

FIELD: chemistry.

SUBSTANCE: invention relates to sorbents for high-performance liquid chromatography (HPLC), in particular to production of chemically modified sorbents. It is a sorbent based on silica gel with grafted through spacer hybrid chiral selector. This sorbent is obtained by modification of silica gel by epoxy groups, eremomycin and bovine serum albumin.

EFFECT: sorbent exhibits high enantioselectivity to various compounds, including while their analysis in biological fluids.

2 cl, 4 dwg, 2 tbl

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RU 2 592 893 C2

Authors

Shpigun Oleg Alekseevich

Shapovalova Elena Nikolaevna

Staroverov Sergej Mikhajlovich

Fedorova Irina Aleksandrovna

Dates

2016-07-27Published

2014-12-26Filed