METHOD FOR TREATING ARTERIAL HYPERTENSION BY INHALATION DELIVERY OF HYPOTENSIVE PREPARATION AEROSOL Russian patent published in 2016 - IPC A61K31/4422 A61K9/12 A61K9/72 A61M11/00 A61P9/12 B82B3/00 B82Y5/00 

FIELD: medicine.

SUBSTANCE: present invention relates to medicine, particularly to a method for treating arterial hypertension in mammals, including humans, and can be used for emergency treatment of acute hypertension conditions, for example, hypertensive crisis. Disclosed method involves the pulmonary administration of aerosol hypotensive preparation in a therapeutically effective amount consisting of calcium antagonist group in nano-sized aerosol form with the particle size of 5-200 nm and their concentration in the range of 10³-10⁸ cm^-3. Nifedipine or nisoldipin is used as a hypotensive preparation.

EFFECT: technical result: is fast reduction (by 25 %) of blood pressure by inhalation delivery of a drug in the form of nano-sized aerosol, higher efficiency of arterial hypertension treatment due to high bioavailability of used preparations in nano-sized aerosol form and reduction of their therapeutic dose.

1 cl, 7 dwg, 4 tbl