ENTERIC-COATED TABLET Russian patent published in 2016 - IPC A61K31/451 A61K9/22 A61K47/02 A61K47/30 A61K47/38 

Abstract RU 2593771 C2

FIELD: pharmaceutics.

SUBSTANCE: present invention relates to pharmaceutics. Described is an enteric-coated tablet containing a tablet core and an enteric coating layer. Core of tablet contains 4-[2-(4-methylphenylsulphanyl)phenyl]piperidine or a pharmacologically acceptable salt thereof. Enteric coating layer contains: a) a polymer ingredient, which is a copolymer of methacrylic acid; b) talc in amount of 10 % to 40 wt% of weight of said polymer ingredient; c) does not contain an alkaline ingredient and d) a plasticiser. Weight of said polymer ingredient in relation to surface area of core of tablet ranges from 4 to 8 mg/cm2.

EFFECT: invention provides improved acid resistance of preparation and high bioavailability of active ingredient of oral tablet.

4 cl, 18 tbl, 15 ex

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RU 2 593 771 C2

Authors

Misaki Masafumi

Tsusima Yuki

Niva Masakhiro

Dates

2016-08-10Published

2011-04-28Filed