FIELD: bioengineering.
SUBSTANCE: new anticancer antibodies are suggested, they link with a human frizzled receptor. Besides new epitopes as the components of human frizzled receptors are identified, they are suitable targets for anticancer agents. Besides, the methods of the antibodies use for the inhibition of a signal path through Wnt and/or inhibition of the tumour growth. The suggested group of inventions can be used in medicine.
EFFECT: higher efficiency of the compositions use.
20 cl, 46 dwg, 15 tbl, 25 ex
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Authors
Dates
2016-04-10—Published
2009-09-28—Filed