IMMUNOSTIMULATING PREPARATION POSSESSING ANTI-TUMOR ACTIVITY Russian patent published in 2016 - IPC A61K39/40 A61K39/02 A61P35/00 A61P37/02 

Abstract RU 2597837 C1

FIELD: pharmacology.

SUBSTANCE: invention refers to pharmacology, namely to a preparation for stimulating anti-tumor immunity or therapy of oncological diseases. Preparation for stimulating anti-tumor immunity or therapy of oncological diseases is characterized by that the main component contains a mixture of native or inactivated corpuscular antigens obtained by at least three culture strains of pale treponema belonging to different antigen groups of the agent. Method for producing the preparation involves preparation of inoculum of at least three strains of culture treponemas, production of biomass of microbes in a liquid nutrient medium, concentration of the obtained microbial suspensions, thermal inactivation of the concentrated native suspensions, their conservation and purification, followed by mixing. Method for stimulating anti-tumor immunity includes parenteral administration of the preparation in a pharmaceutically acceptable amount. Method of oncological diseases therapy includes parenteral administration of the preparation in a pharmaceutically acceptable amount.

EFFECT: above described invention expands the range of immunomodulatory agents with anti-tumor activity.

19 cl, 1 dwg, 14 tbl, 9 ex

Similar patents RU2597837C1

Title Year Author Number
POLYVALENT CORPUSCULAR ANTIGEN FOR PRODUCTION OF MEDICAL AND PREVENTIVE BIOLOGICAL PRODUCTS FOR BRUCELLOSIS 2006
  • Gavrilova Larisa Borisovna
  • Okhapkina Veronika Jur'Evna
  • Shabalin Boris Aleksandrovich
  • Kuznetsov Sergej Mikhajlovich
RU2330681C1
TESTICULAR VACCINE AS AN ANTITUMOUR PROPHYLACTIC AGENT 2021
  • Seledtsov Viktor Ivanovich
  • Kelin Leonid Valentinovich
  • Seledtsova Galina Viktorovna
RU2784803C1
PROTEIN-PEPTIDE ANTITUMOR COMPOSITION, CELL PREPARATION ACTIVATED THEREWITH AND METHOD FOR TUMOR PROPHYLAXIS OR TREATMENT 2004
  • Kalinina Ekaterina Sergeevna
  • Lutsenko Elena Valer'Evna
  • Lutsenko Sergej Viktorovich
  • Severin Evgenij Sergeevich
  • Severin Sergej Evgen'Evich
  • Fel'Dman Natalija Borisovna
  • Khomjakova Anastasija Viktorovna
RU2283129C1
VACCINE COMPOSITIONS, METHODS FOR APPLICATION THEREOF IN MELANOMA PREVENTION AND TREATMENT, AND GENETIC CONSTRUCTIONS FOR OBTAINING ACTIVE SUBSTANCES OF COMPOSITION 2006
  • Digtjar' Anton Vasil'Evich
  • Lutsenko Elena Valer'Evna
  • Lutsenko Sergej Viktorovich
  • Pozdnjakova Natal'Ja Vladimirovna
  • Severin Evgenij Sergeevich
  • Severin Sergej Evgen'Evich
  • Solov'Ev Andrej Ivanovich
  • Fel'Dman Natalija Borisovna
  • Khomjakova Anastasija Viktorovna
RU2333767C2
METHOD FOR ACTIVATION OF CYTOTOXIC LYMPHOCYTES 2019
  • Chernysh Sergej Ivanovich
  • Tulin Dmitrij Valentinovich
RU2751837C2
POLYVALENT CATTLE VACCINE AGAINST ANAEROBIC ENTEROTOXEMIA AND METHOD OF USING IT 2017
  • Pimenov Nikolaj Vasilevich
  • Kolesnikova Yuliya Nikolaevna
  • Kapustin Andrej Vladimirovich
RU2699035C2
VACCINE AND METHOD FOR INCREASING IMMUNOGENICITY AND SPECIFIC ACTIVITY OF INFECTION PREVENTION AGENTS 2020
  • Abidov Musa Tazhudinovich
  • Abidova Alina Musaevna
  • Stepanov Aleksandr Valentinovich
  • Kurochka Valerij Kuzmich
  • Altudov Yurij Kambulatovich
  • Filatov Nikolaj Nikolaevich
RU2741834C1
CELL LINE OF HUMAN KIDNEY CANCER IBGVAT R 6 2014
  • Lysjuk Elena Jur'Evna
  • Lukashina Marina Igorevna
  • Kibardin Aleksej Vladimirovich
  • Gnuchev Nikolaj Vasil'Evich
  • Georgiev Georgij Pavlovich
  • Tkachenko Svetlana Viktorovna
  • Ol'Shanskaja Julija Vjacheslavovna
  • Konovalov Dmitrij Mikhajlovich
  • Larin Sergej Sergeevich
RU2573940C1
MIXED VACCINE AGAINST ROTA-, CORONA-, HERPESVIRAL AND ESCHERICHIA DIARRHEA IN NEWBORN CALVES 1999
  • Gaffarov Kh.Z.
  • Spiridonov G.N.
  • Ivanov A.V.
  • Romanov E.A.
  • Khabibullin F.Sh.
RU2145236C1
CELL LINE OF HUMAN KIDNEY CANCER IBGVAT R 27 2014
  • Lysjuk Elena Jur'Evna
  • Lukashina Marina Igorevna
  • Kibardin Aleksej Vladimirovich
  • Gnuchev Nikolaj Vasil'Evich
  • Georgiev Georgij Pavlovich
  • Tkachenko Svetlana Viktorovna
  • Ol'Shanskaja Julija Vjacheslavovna
  • Konovalov Dmitrij Mikhajlovich
  • Larin Sergej Sergeevich
RU2573938C1

RU 2 597 837 C1

Authors

Mordukhovich Eduard Isaakovich

Zhukov David Borisovich

Darmov Ilya Vladimirovich

Okhapkina Veronika Yurevna

Dates

2016-09-20Published

2015-04-24Filed