CONJUGATES AND COMPOSITIONS FOR IMMUNOTHERAPY AND ANTICANCER TREATMENT Russian patent published in 2016 - IPC C07K19/00 C07K14/775 C07K14/54 C07K14/715 C12N15/62 C12N15/63 C12N5/10 C12N5/783 A61K38/17 A61K48/00 A61P37/04 A61P35/00 

Abstract RU 2597989 C2

FIELD: biotechnology.

SUBSTANCE: invention refers to immunology, and can be used in medicine. Composition based on combined application of ApoA, interleukin 15 and Sushi domain alpha chain of IL15 receptor, is used for anti-tumour immune response in individual.

EFFECT: use of ApoA1 together with IL15 and Sushi IL15ra domain provides synergetic effect on stimulating anti-tumour immune response in mammal by intensifying expansion of anticancer CTL.

18 cl, 13 dwg, 13 ex

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RU 2 597 989 C2

Authors

Berraondo Lopes Pedro

Foravanti Dzhessika

Medina Echevers Khose

Melero Bermekho Ignasio Khaver

Ochoa Neto Mariya Del Karmen

Palason Garsia Fransisko De Asis

Bulfone-Paus Silviya

Dejtman Ervin Khans

Dates

2016-09-20Published

2010-12-10Filed