FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to ophthalmology, and aims for treating of experimental retinopathy of prematurity (ERP). To newborn rats against changing of oxygen concentration in the inhaled air from 60 to 15 % each 12 hours at a constant light and temperature conditions in the first 14 days of postnatal period daily in intra peritoneal way is introduced melatonin solution in dose 10 mg/kg in an volume of 30 mcl.
EFFECT: using of the invention provides normalizing of a blood-retinal barrier and antioxidant status in the vitreous body of rats with ERP against intraperitoneal introduction of melatonin during violation of postnatal development and maturation of retinal vascular system.
1 cl, 2 tbl, 6 ex
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