FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to ophthalmology, and can be used to predict the development of extraretinal vasoproliferation in experimental retinopathy of prematurity (ROP). On the 14th day of life in rat pups with a PH model, the content of L-deoxyphenylalanine (L-DOPA) is determined in the blood plasma. When its level is equal to or below 0.31 ng/ml, the development of ROP is predicted.
EFFECT: invention provides the possibility of predicting the risk of developing extraretinal vasoproliferation in experimental retinopathy of prematurity in a rat model of the disease in order to substantiate the possibility of laboratory screening of ROP in the clinic by determining the level of L-DOPA in the blood plasma of rat pups with ROP model on the 14th day of the experiment.
1 cl, 1 tbl, 4 ex
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