TISSUE-REGENERATION PROMOTER USING RECRUITMENT OF BONE MARROW MESENCHYMAL STEM CELLS AND/OR PLURIPOTENT STEM CELLS IN BLOOD Russian patent published in 2016 - IPC A61K35/28 A61K38/00 A61K48/00 A61P17/00 A61P19/00 A61P25/00 A61P43/00 C07K14/47 

Abstract RU 2599448 C2

FIELD: medicine.

SUBSTANCE: presented inventions relate to use of an agent stimulating tissue regeneration, and a method of stimulating repair of mesenchymal or epithelial neurological tissues by administering said agent. Described agent is an S100A8 protein, a cell which secretes an S100A8 protein, a vector into which DNA encoding S100A8 protein is inserted, an S100A9 protein, a cell which secretes an S100A9 protein or a vector into which DNA encoding an S100A8-9 protein is inserted.

EFFECT: presented inventions can be used for inducing healing of injured tissues by recruiting bone-marrow-derived cells in area of damage, thereby treating such diseases as extensive pitting skin, bone fractures, cerebral infarction.

7 cl, 44 dwg, 1 tbl, 9 ex

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RU 2 599 448 C2

Authors

Tamai Katsuto

Kaneda Yasufumi

Yamadzaki Takekhiko

Tino Takenao

Saga Kotaro

Endo Mayumi

Dates

2016-10-10Published

2010-10-28Filed