FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine, namely to laboratory diagnostics, and can be used for the in vitro prognosis of progression of an HIV-1 (human immunodeficiency virus type 1) infection in a patient infected with an HIV-1 virus. It is performed by the following steps: a) measuring the level of antibodies directed against the 3S peptide of SEQ ID N° 2in a sample collected from the said patient, b) comparing the level of anti-3S antibodies measured at step a) with a reference value of anti-3S antibody level, that is indicative of the progression of the HIV-1 infection, wherein (I) level is a "good" prognosis of HIV disease progression for values measured at step a) that are above the said reference value, or (II) level is a "bad" prognosis of HIV disease progression for values measured at step a) that are below the said reference value. Also a method for monitoring the efficacy of a therapeutic treatment for HIV-1 is suggested.
EFFECT: group of inventions enables to prognose the progression of disease caused by HIV-1, in the general population of HIV infected patients.
8 cl, 6 dwg, 2 tbl, 1 ex
Title | Year | Author | Number |
---|---|---|---|
COMPOSITION FOR PREVENTING AND/OR TREATING INFECTION, CAUSED BY HIV-1 | 2012 |
|
RU2603262C2 |
ANTIBODY OR FRAGMENT THEREOF WITH HIV-NEUTRALISING ACTIVITY | 2005 |
|
RU2380378C2 |
ANTIBODY OR FRAGMENT THEREOF, HAVING NEUTRALISING EFFECT ON HIV, BUT NOT ON IL2 | 2005 |
|
RU2393873C2 |
BIOMARKERS AND APPLICATIONS IN TREATING VIRAL INFECTIONS, INFLAMMATIONS OR CANCER | 2019 |
|
RU2820481C2 |
METHOD OF PREDICTING PROGRESSION OF HIV INFECTION IN PATIENTS RECEIVING ANTIRETROVIRAL THERAPY | 2019 |
|
RU2697392C1 |
PROADM FOR PREDICTING RISK OF CONDITION REQUIRING HOSPITALIZATION IN PATIENTS WITH SYMPTOMS OF INFECTIOUS DISEASE | 2019 |
|
RU2820944C2 |
QUINOLINE DERIVATIVES FOR USE IN TREATING OR PREVENTING VIRAL INFECTION | 2016 |
|
RU2723016C2 |
HBHA-DETECTION OF TUBERCULOSIS AND MYCOBACTERIUM TUBERCULOSIS INFECTION | 2005 |
|
RU2426128C2 |
NOVEL QUINOLINE DERIVATIVE FOR USE IN TREATING AND PREVENTING VIRAL INFECTIONS | 2016 |
|
RU2723013C2 |
COMPOSITIONS AND METHODS USED FOR ASSESSING CYTOTOXICITY OF SINGLE CELLS | 2009 |
|
RU2532228C2 |
Authors
Dates
2016-11-10—Published
2012-02-21—Filed