IMMUNOPROPHYLACTIC VACCINE AGAINST HIV BASED ON HIV-SPECIFIC ANTIBODIES Russian patent published in 2014 - IPC C12N15/10 A61K39/21 A61P31/18

Abstract RU 2505604 C2

FIELD: biotechnologies.

SUBSTANCE: there proposed is the method for obtaining vaccine against HIV-1 with the use of method of reverse paning at bacterial virus-presented library of HIV-1 - specific scFv antibodies obtained on the basis of mRNA B-lymphocytes of the patients infected by HIV-1 and enriched via paning on HIV-1 peptides and induced systems of expression of recombinant proteins with eukaryotic glycosylation. There also reviewed is the vaccine against HIV-1 and its use for immunisation of non-infected people against infection and development of HIV infection.

EFFECT: HIV-1 vaccine obtained due to this invention provides the appearance of immune response in organism with formation of HIV-1-specific antibodies.

12 cl, 27 dwg, 9 tbl, 4 ex

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RU 2 505 604 C2

Authors

Filinova Elena Ju.

Dates

2014-01-27—Published

2008-10-09—Filed