FIELD: chemistry.
SUBSTANCE: invention relates to a luliconazole crystal presented by formula, wherein crystal has such a crystal habit, that (021) plane is its characteristic plane of crystal growth, in which I(021) in relation to total I(001), I(100), I(10-1), I(011), I(110), I(11-1), I(10-2), I(11-2), I(020), I(021), I(20-2), I(121), I(013), I(11-3) and I(221) is not less than 1/3, provided that relative to diffraction peaks, detected in range of 2θ=5-35° in x-ray powder diffraction using CuKα radiation, integral intensities of diffraction peaks, which correspond to (001), (100), (10-1), (011), (110), (11-1), (10-2), (11 -2), (020), (021), (20-2), (121), (013), (11-3) and (221) planes are designated as I(001), I(100), I(10-1), I(011), I(110), I(11-1), I(10-2), I(11-2), I(020), I(021), I(20-2), I(121), I(013), I(11-3) and I(221) respectively .
EFFECT: invention aims at providing means to improve solubility of luliconazole.
8 cl, 6 dwg, 4 tbl, 4 ex
Authors
Dates
2016-12-10—Published
2012-11-02—Filed