METHOD OF THERAPY OF MALIGNANT GROWTHS Russian patent published in 2016 - IPC A61K31/727 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncology, and can be used in treating malignant growths. Method involves chemotherapy and subcutaneous injection of Enoxaparin sodium. Before the beginning of chemotherapy patient's peripheral blood is examined to determine the level of D-dimer and if its value in the range of 1-3, 8 mcg/kg introduction of Enoxaparin sodium is prescribed in an amount of 15-25 mg for 7-10 days, and if a value of 3.9-6.5 mcg/ml introduction of Enoxaparin sodium is prescribed in an amount of 35-45 mg for 7-10 days, in determining the pre-therapeutic value of D-dimer above 6.5 mcg/ml, prescribed the introduction of Enoxaparin sodium in an amount of 35-45 mg/kg for 10-14 days. Then on the last day of injection of Enoxaparin sodium is again determined level of D-dimer and if the value below 1 mcg/ml, further therapy by Enoxaparin sodium not continued, if determining the level of d-dimer equal to and above 1 mcg/ml, repeated therapy by Enoxaparin sodium is described in accordance with the above values of D-dimer.

EFFECT: using the invention enables to increase clinical effectiveness of treatment ensured by individual daily dosage of Enoxaparin sodium and reduce a risk of profuse bleeding.

1 cl, 3 ex