FIELD: medicine.
SUBSTANCE: present inventionrelates to inhalation powder composition. Powder composition comprises finely ground particles with average particle diameter of 20 mcm or less including pirfenidone, excipient and carrier with average particle diameter of 10 to 200 mcm. Excipient is represented by one or more substances selected from group consisting of saccharides, sugar alcohols, fatty acids and salts thereof, waxes, calcium sulphate, calcium carbonate, talc and titanium oxide. Carrier is represented by saccharide or sugar alcohol. Excipient is preferably represented by erythritol and carrier is represented by lactose. Method of producing inhalation powder composition is also described.
EFFECT: inhalation powder composition according to invention reduces risk of photodermatosis side effect induced by drug pirfenidonom and in better way in comparison with orally introduced composition.
15 cl, 8 dwg, 4 tbl, 7 ex
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