METHOD OF DIFFERENTIAL DIAGNOSTIC OF URETHRITIS IN MALES Russian patent published in 2016 - IPC A61B8/06 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely, to dermatovenerology, and can be used for differential diagnosis of specific and nonspecific urethritis in males. Used an endoscopic probe using a helium-neon laser at wave length 0.63 mcm for laser doppler flowmetry. Probe is installed directly in urethra until the transition of anterior part to the rear. Carry out analysis of changes in the microcirculation at the graphical recording and parameters are calculated by formula

$$I=\frac{M}{3\sigma }\left(\frac{A_{\max \alpha }}{F_{\max \alpha }}-\mathrm{1,3}\frac{A_{\max LF}}{F_{\max LF}}+\mathrm{1,7}\frac{A_{\max HF}}{F_{\max HF}}\right)-\mathrm{4,9}\frac{A_{\max CF}}{F_{\max CF}},$$

where I - microcirculation index, which reflects the link of microcirculation indicators with amplitude-frequency spectrum, M - the microcirculation index in perfusion units, σ - mean square deviation, A_max - maximum amplitude in each of band oscillations amplitude-frequency spectrum, F_max - maximum frequency of oscillation in each group, α-slow rhythms 1-3 cycles per minute, LF - slow rhythms 4-12 cycles per minute, HF-fast rhythms 12-36 cycles per minute, CF - pulse oscillations. When microcirculation index of 6.0 units is diagnosed urethritis, caused by opportunistic flora. When microcirculation index of 2.7 units-urethritis, caused by pathogenic microorganisms.

EFFECT: method provides simplifying of the differential diagnosis of urethritis by assessing the state of microcirculation in urethra depending on etiological agent provides early diagnosis of hemodynamic and microcirculatory disorders associated with pathological process in the urethra.

1 cl, 2 tbl, 2 ex