FIELD: medicine.
SUBSTANCE: invention relates to virology. Disclosed is a vaccine strain V/60/Phuket/2013/26-reassortant, obtained by genetic reassortation of epidemic virus V/Phuket/3073/2013 with cold-adapted temperature-sensitive virus V/USSR/60/69 - attenuation donor, safe for humans. Strain of V/60/Phuket/2013/26 is characterised by temperature sensitivity and cold adaptation and safety for laboratory animals. Strain of V/60/Phuket/2013/26 comprises genes which code surface virus antigens of hemagglutinin (HA) virus and neuraminidase (NA), from an epidemic parent virus V/Phuket/3073/2013 and remaining six genes coding internal non-glycosylated proteins, from attenuation donor V/USSR/60/69.
EFFECT: strain of V/60/Phuket/2013/26 can be used in medicine for preventing influenza incidence in adults and children in live influenza intranasal vaccine.
1 cl, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
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RU2746274C2 |
| INFLUENZA VIRUS STRAIN B/60/MASSACHUSETTS/2012/10 FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2013 |
|
RU2546190C1 |
| VACCINATING INFLUENZA VIRUS STRAIN B/60/WISCONSIN/2010/125 | 2012 |
|
RU2545695C2 |
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|
RU2757397C1 |
| VACCINE STRAIN OF INFLUENZA VIRUS B/60/HONG KONG/ 2017/5584 (VICTORIA LINE) FOR THE PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2021 |
|
RU2757396C1 |
| VACCINE INFLUENZA VIRUS A/17/SOUTH AFRICA/2013/01 (H1N1)PDM09 FOR PRODUCTION OF LIVE INTRANASAL INFLUENZA VACCINE FOR ADULTS AND CHILDREN | 2016 |
|
RU2627188C1 |
| VACCINE INFLUENZA VIRUS STRAIN A/17/Bolivia/2013/6585 (H1N1)pdm09 FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2015 |
|
RU2605314C1 |
| COLD-ADAPTED ATTENUATION DONOR, STRAIN OF INFLUENZA VIRUS B/SSSR/60/69/5252, INTENDED FOR PRODUCTION OF STRAINS OF LIVE INTRANASAL INFLUENZA VACCINE | 2021 |
|
RU2769672C1 |
| INFLUENZA VIRUS STRAIN A/17/Anui/2013/61 (H7N9) FOR PRODUCTION OF LIVE INTRANASAL INFLUENZA VACCINE | 2013 |
|
RU2563351C2 |
| VACCINE STRAIN OF INFLUENZA A/17/NEW YORK/15/5364 (H1N1) PDM09 FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2017 |
|
RU2653388C1 |
