FIELD: biotechnology.
SUBSTANCE: submitted strain A/17/South Africa/2013/01 (H1N1)pdm09 is a reassortant obtained by crossing of wild virus A/South Africa/3626/2013 (H1N1)pdm09 with virus A/Leningrad/134/17/57 (H2N2) - donor of attenuation, harmless to humans. The strain of live influenza A/17/South Africa/2013/01 (H1N1)pdm09 is characterised by a set of symptoms: antigenic specificity of the epidemic virus A/17/South Africa/3626/2013 (H1N1)pdm09, temperature sensitivity and cold adaptation, harmless to laboratory animals, which correlates with human attenuation. The reassortant has inherited the genes coding surface virus antigens - hemagglutinin (HA) and neuraminidase (NA) from the epidemic parent virus, and six genes coding internal non-glycosylated proteins from the attenuation donor.
EFFECT: strain can be used in practical health care to prevent the incidence of influenza in adults and children.
5 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| VACCINE INFLUENZA VIRUS STRAIN A/17/Bolivia/2013/6585 (H1N1)pdm09 FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2015 |
|
RU2605314C1 |
| VACCINE STRAIN OF INFLUENZA A/17/NEW YORK/15/5364 (H1N1) PDM09 FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2017 |
|
RU2653388C1 |
| VACCINE STRAIN OF INFLUENZA VIRUS A/17/SLOVENIA/2015/1121 (H1N1)PDM09 FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2019 |
|
RU2724706C1 |
| VACCINE STRAIN OF INFLUENZA VIRUS A/17/BRISBANE/2018/8175 (H1N1) PDM09 FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2019 |
|
RU2735291C1 |
| REASSORTANT STRAIN OF INFLUENZA VIRUS A/17/VICTORIA/2019/276 (H1N1) PDM09 FOR THE PRODUCTION OF LIVE INTRANASAL INFLUENZA VACCINE FOR ADULTS AND CHILDREN | 2022 |
|
RU2783878C1 |
| REASSORTANT STRAIN OF INFLUENZA VIRUS A/17/GUANGDONG-MAONAN/2019/211 (H1N1)PDM09 FOR PRODUCTION OF LIVE INTRANASAL INFLUENZA VACCINE FOR ADULTS AND CHILDREN | 2022 |
|
RU2793387C1 |
| REASSORTANT STRAIN OF INFLUENZA A/17/DARWIN/2018/154 (H1N1)PDM09 VIRUS FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2023 |
|
RU2825670C1 |
| REASSORTANT STRAIN OF INFLUENZA A/17/IOWA/2018/5388 (H1N1)PDM09 VIRUS FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2023 |
|
RU2825671C1 |
| STRAIN OF INFLUENZA VIRUS A/17/INDIANA/11/72 (H3N2v) FOR PRODUCTION OF LIQUID INFLUENZA INTRANASAL VACCINE FOR ADULTS AND FOR CHILDREN | 2013 |
|
RU2545706C1 |
| VACCINE STRAIN OF FLU VIRUS A/17/CALIFORNIA/2009/38 (H1N1) FOR PROFUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2009 |
|
RU2413765C1 |
