VACCINE INFLUENZA VIRUS STRAIN A/17/Bolivia/2013/6585 (H1N1)pdm09 FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN Russian patent published in 2016 - IPC C12N7/00 A61K39/145 

Abstract RU 2605314 C1

FIELD: medicine.

SUBSTANCE: invention refers to medical virology and concerns influenza virus strain. Characterized vaccine strain A/17/Bolivia/2013/6585 (H1N1)pdm09 - reassortant, produced by crossing "wild" virus A/Bolivia/559/2013 (H1N1)pdm09 with cold-adapted heat-sensitive virus A/Leningrad/134/17/57 (H2N2) - donor of attenuation, safe for humans. Strain A/17/Bolivia/2013/6585 (H1N1)pdm09 actively propagated in developing chicken embryos at optimal temperature of 32 °C, characterised by thermal sensitivity and cold adaptation and safety for laboratory animals. Reassortant deposited in State collection of viruses of FGBU "FNICEM nam. N.F. Gamalei" of the Ministry of health of Russia Research Institute of virology. D. I. Ivanovskogo under №2809.

EFFECT: invention can be used in practical health services for preventing influenza incidence in adults and children.

1 cl, 5 tbl

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Authors

Bazhenova Ekaterina Andreevna

Kiseleva Irina Vasilevna

Kuznetsova Viktorija Arkadevna

Fedorova Ekaterina Alekseevna

Rudenko Larisa Georgievna

Dates

2016-12-20Published

2015-10-23Filed