LIXISENATIDE AS ADD-ON THERAPY TO BASAL INSULIN IN TYPE 2 DIABETES Russian patent published in 2017 - IPC A61K38/26 A61K38/28 A61P3/10 A61P3/04 A61K31/155 

Abstract RU 2606154 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to glycemic control in diabetes type 2 patients with glucose concentration 2 hours after meal at least 14 mmol/l, glycaemia in whom is not controlled properly only by basal insulin. There are disclosed: a pharmaceutical combination for use at the specified purpose, containing lixisenatide (AVE0010, desPro36Exendin-4(1-39)-Lys6-NH2 and/or its pharmaceutically acceptable salt), basal insulin or pharmaceutically acceptable salt thereof, and a corresponding method for improving glycemic control; combination and method can optionally include metformin or its salt.

EFFECT: technical result consists in implementing the declared application and significant reduction of HbA1c glycated hemoglobin.

17 cl, 35 tbl, 13 dwg

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RU 2 606 154 C2

Authors

Nimeller Elizabet

Silvestr Luiz

Boka Gabor

Miossek Patrik

Dates

2017-01-10Published

2012-05-11Filed