DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE Russian patent published in 2017 - IPC C07D215/54 A61K31/4704 A61P35/00 A61P37/02 

Abstract RU 2608306 C2

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, specifically to deuterium-enriched 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)-phenyl]-1,2-dihydroquinoline-3-carboxamide. Invention also relates to a pharmaceutical composition based on deuterium-enriched carboxamide, method for production thereof and method of treating malignant hyperproliferative disorder or autoimmune disease, based on use of deuterium-enriched carboxamide.

EFFECT: technical result is obtaining deuterium-enriched 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)-phenyl]-1,2-dihydroquinoline-3-carboxamide, having useful biological properties.

25 cl, 7 dwg, 10 tbl, 1 ex

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RU 2 608 306 C2

Authors

Svenson Lejf

Dates

2017-01-17Published

2012-06-20Filed