FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to novel horse allergens, and can be used in medicine for prophylactic or therapeutic treatment or diagnostics of type I allergy in horses. Horse allergen is obtained, which represents secretoglobin with molecular weight of 15 kDa in non-reducing conditions and contains first peptide chain with molecular weight of approximately 5 kDa and second peptide chain with molecular weight of approximately 10 kDa, linked to each other. Recombinant form of said allergen is also obtained.
EFFECT: invention enables to obtain recombinant horse allergen with completely determined amino acid sequence.
13 cl, 10 dwg, 3 tbl, 8 ex
Title | Year | Author | Number |
---|---|---|---|
NEW PROSTATE KALLIKREIN ALLERGEN | 2007 |
|
RU2502074C2 |
ALLERGENS PRODUCED BY RECOMBINANT METHODS | 2010 |
|
RU2592674C2 |
HOUSE DUST MITE PROTEIN | 2007 |
|
RU2570563C2 |
ANTIGEN MOLECULAR MASSIFS | 2003 |
|
RU2324704C2 |
COMPOSITION AND IMMUNIZATION METHOD, METHODS FOR PRODUCING NON-NATURAL, ORDERED AND REPEATED ANTIGEN MASSIVE AND COAT PROTEIN | 2002 |
|
RU2295973C2 |
COMPOSITION AND METHOD FOR IMMUNIZATION, METHOD FOR PRODUCING OF NON-NATURAL, ORDERED AND REPEATED ANTIGEN MASSIVE | 2002 |
|
RU2294211C2 |
METHOD OF IDENTIFYING ALLERGENIC PROTEINS AND PEPTIDES | 2009 |
|
RU2519674C2 |
HUMAN ANTIBODIES TO Fel d1 AND METHODS OF USE THEREOF | 2013 |
|
RU2658491C2 |
RECOMBINANT POLYPEPTIDE BASED ON BIRCH POLLEN ALLERGEN AND APPLE ALLERGEN AS AN ALLERGY VACCINE | 2020 |
|
RU2761431C1 |
COMPOSITION AND METHOD FOR IMMUNISATION, METHOD OF PRODUCING UNNATURAL, ORDERED AND REPEATING MASSIVE OF ANTIGENS | 2002 |
|
RU2438701C2 |
Authors
Dates
2017-01-18—Published
2011-04-26—Filed