FIELD: bioengineering.
SUBSTANCE: suggested: house dust mite protein being polypeptide containing definite amino acid sequence, described in the list of sequences; polypeptide coding DNA molecule; expression vector on its base, and transformed by it recombinant cell for polypeptide expression. Described: vaccinal composition for immunotherapy of allergy response to house dust mites based on the polypeptide; use of said polypeptide to diagnose allergy response to house dust mites; options of polypeptide use during medicament production: for immunotherapy of allergy response to house dust mites or to prevent allergisation by house dust mite protein.
EFFECT: invention ensures polypeptide that can be used both in diagnostics, and in therapy of allergy response to house dust mites.
13 cl, 6 dwg, 2 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| HYBRID PEPTIDE CARRYING PROTEINS AS VACCINES AGAINST ALLERGY | 2012 |
|
RU2630652C2 |
| NEW MUTANT ALLERGENS | 2001 |
|
RU2285042C2 |
| TREATMENT AND PREVENTION OF ALLERGY TO HOUSE DUST MITES | 2019 |
|
RU2815386C2 |
| NEW WHEAT ALLERGENS | 2008 |
|
RU2502742C2 |
| IMMUNOREGULATORY VACCINE | 2013 |
|
RU2650709C2 |
| MODULATION OF ANTIGEN IMMUNOGENICITY BY DELETING EPITOPES RECOGNIZED BY NKT-CELLS | 2011 |
|
RU2598247C2 |
| HYPOALLERGENIC VARIANTS OF MAL D 1, MAIN MALUS DOMECTICA ALLERGEN | 2012 |
|
RU2624030C2 |
| RECOMBINANT POLYPEPTIDE BASED ON BIRCH POLLEN ALLERGEN AND APPLE ALLERGEN AS AN ALLERGY VACCINE | 2020 |
|
RU2761431C1 |
| METHOD OF IDENTIFYING ALLERGENIC PROTEINS AND PEPTIDES | 2009 |
|
RU2519674C2 |
| ANTIGEN MOLECULAR MASSIFS | 2003 |
|
RU2324704C2 |
