RECOMBINANT POLYPEPTIDE BASED ON BIRCH POLLEN ALLERGEN AND APPLE ALLERGEN AS AN ALLERGY VACCINE Russian patent published in 2021 - IPC A61K39/35 A61K39/36 A61K39/29 A61P37/08 C07K14/02 

Abstract RU 2761431 C1

FIELD: allergy treatment.

SUBSTANCE: invention relates to a recombinant polypeptide for the treatment and prevention of allergy to birch pollen and apple containing peptide fragments of the allergens Bet vl and Mal d 1 fused with the hepatitis B virus polypeptide PreS, represented by the amino acid sequence SEQ ID NO: 2, as well as to a vaccine composition for the treatment or prevention of allergy to birch pollen and apple containing an effective amount of the above recombinant polypeptide.

EFFECT: extension of the range of preparations against allergy.

2 cl, 6 ex, 12 dwg, 2 tbl

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RU 2 761 431 C1

Authors

Khaitov Musa Rakhimovich

Valenta Rudolf

Veber Milena

Kampana Raffaella

Shilovskij Igor Petrovich

Smirnov Valerij Valerevich

Zhernov Yurij Vladimirovich

Andreev Sergej Mikhajlovich

Shatilov Artem Andreevich

Timofeeva Anastasiya Vitalevna

Ilina Natalya Ivanovna

Fedenko Elena Sergeevna

Elyusitina Olga Gurevna

Trukhin Viktor Pavlovich

Yudin Sergej Mikhajlovich

Skvortsova Veronika Igorevna

Dates

2021-12-08Published

2020-10-26Filed