IMMUNOGENIC COMPOSITIONS Russian patent published in 2017 - IPC A61K39/385 A61K39/09 A61P37/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to immunology, and can be used for producing immunogenic composition. Immunogenic composition contains a) conjugate, which is capsular saccharide GBS of serotype Ia conjugated with protein-carrier; b) conjugate, which is capsular saccharide GBS of serotype Ib conjugated with protein-carrier; and c) conjugate, which is capsular saccharide GBS of serotype III conjugated with protein-carrier, where (i) each capsular saccharide GBS is present in an amount of 5 mcg, 10 mcg or 20 mcg per dose unit, (ii) protein-carrier in a), b) and c) is diphtheria or CRM197 toxoid, and iii) immunogenic composition does not contain an adjuvant based on aluminium salts.

EFFECT: use of given composition of immunogenic compositions with effective amounts of polysaccharides GBS of type Ia, Ib and III, conjugated with CRM197, makes it possible to use it as a vaccine for preventing GBS infection in human body.

14 cl, 4 dwg, 21 tbl